The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
Calculated molecular weight
147 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Monoclonal
Host species
Rabbit
Immunogen
Recombinant protein of human Collagen VI
Observed molecular weight
109 kDa
Alias
OPLL; BTHLM1; UCHMD1
Cat Number: RMA02537
Collagen VI Recombinant Rabbit mAb
Applications:
ICC/IFIHCWB
Species Reactivity:
HumanMouseRat
$ 229
/ 50ul
In Stock
50ul100ul
Description
Product Features
Applications
ICC/IFIHCWB
Species Reactivity
HumanMouseRat
Uniprot
P12109
GeneID
1291
Isotype
IgG
Background
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]