This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]
Calculated molecular weight
35 kDa
Purification method
Affinity Purification
Conjugate
Un-conjugated
Clonality
Monoclonal
Host species
Rabbit
Immunogen
A synthetic peptide of human NDUFAF1
Observed molecular weight
38 kDa
Alias
CGI65; CIA30; CGI-65
Cat Number: RMA01049
NDUFAF1 Recombinant Rabbit mAb
Species Reactivity:
HumanMouseRat
Applications:
FCICC/IFIHCIPWB
$ 229
/ 50μl
In Stock
50μl100μl
Description
Product Features
Species Reactivity
HumanMouseRat
Applications
FCICC/IFIHCIPWB
Uniprot
Q9Y375
GeneID
51103
Isotype
IgG
Background
This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]