This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]
预测分子量
64.4 kDa
纯化方式
Affinity Purification
克隆性
Monoclonal
来源
Mouse
免疫源
Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq]
预测分子量
64.4 kDa
纯化方式
Affinity Purification
克隆性
Monoclonal
来源
Mouse
免疫源
Full length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.