The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Calculated molecular weight
23.6 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human CDKN3(NP_005183) produced in HEK293T cell.
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Calculated molecular weight
23.6 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human CDKN3(NP_005183) produced in HEK293T cell.