The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq]
Calculated molecular weight
52.5 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human PPM1B(NP_002697) produced in HEK293 cell.
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq]
Calculated molecular weight
52.5 kDa
Purification method
Affinity Purification
Clonality
Monoclonal
Host species
Mouse
Immunogen
Full length human recombinant protein of human PPM1B(NP_002697) produced in HEK293 cell.