Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP. [supplied by OMIM]
预测分子量
42.9 kDa
纯化方式
Affinity Purification
克隆性
Monoclonal
来源
Mouse
免疫源
Full length human recombinant protein of human PRKAR1B(NP_002726) produced in HEK293T cell.
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP. [supplied by OMIM]
预测分子量
42.9 kDa
纯化方式
Affinity Purification
克隆性
Monoclonal
来源
Mouse
免疫源
Full length human recombinant protein of human PRKAR1B(NP_002726) produced in HEK293T cell.