IHC, WB

Q13515

Affinity Purification

Monoclonal

Human, Rat

Mouse

IgG1

Human recombinant protein fragment corresponding to amino acids 184-415 of human BFSP2 (NP_003562) produced in E.coli.

45.7 kDa

More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex. [provided by RefSeq, Jun 2009]

OTI1D9